ICSI with All Oocytes Recurrent Metaphase I Characterized by Absence Perivitelline Space

Previous cases reported recurrent all oocytes in repeated cycles were arrested at MI failed to mature after culture and ICSI resulted total nonfertilization. Ionomycin induced first PB extrusion patients with maturation-resistant oocytes. combined assisted oocyte activation (AOA) on MII matured vitro abnormal fertilization no further embryo cleavage potential. The objective of this work was research if AOA helpful for In case, patient both retrievaled immature characterized by absence perivitelline space (APVS). the second cycle, ionomycin used perfomed ICSI, again.